Friday, May 16, 2008
By MARILYNN MARCHIONE, AP Medical Writer
Breast cancer patients with low levels of vitamin D were much more likely to die of the disease or have it spread than patients getting enough of the nutrient, a study found — adding to evidence the "sunshine vitamin" has anti-cancer benefits. The results are sure to renew arguments about whether a little more sunshine is a good thing.
The skin makes vitamin D from ultraviolet light. Too much sunlight can raise the risk of skin cancer, but small amounts — 15 minutes or so a few times a week without sunscreen — may be beneficial, many doctors believe.
While the vitamin is found in certain foods and supplements, most don't contain the best form, D-3, and have only a modest effect on blood levels of the nutrient. That's what matters, the Canadian study found.
Only 24 percent of women in the study had sufficient blood levels of D at the time they were first diagnosed with breast cancer. Those who were deficient were nearly twice as likely to have their cancer recur or spread over the next 10 years, and 73 percent more likely to die of the disease.
"These are pretty big differences," said study leader Dr. Pamela Goodwin of Mount Sinai Hospital in Toronto. "It's the first time that vitamin D has been linked to breast cancer progression."
But people shouldn't start downing supplements, she warned. Experts don't agree on how much vitamin D people need or the best way to get it, and too much can be harmful. They also don't know whether getting more vitamin D can help when someone already has cancer.
"We have no idea whether correcting a vitamin D deficiency will in any way alter these outcomes," said Dr. Julie Gralow, a cancer specialist at the University of Washington in Seattle.
The study was released Thursday by the American Society of Clinical Oncology and will be presented at the group's annual meeting later this month.
Lots of earlier research suggests vitamin D may help prevent prostate, breast and especially colon cancer. In lab and animal tests, vitamin D stifles abnormal cell growth, curbs formation of blood vessels that feed tumors and has many other anti-cancer effects.
Other evidence: People who live in northern regions of the world have higher cancer rates than those living closer to the equator, possibly because of less sunshine and vitamin D.
The Canadian researchers wanted to see whether it made a difference in survival. They took blood from 512 women at three University of Toronto hospitals between 1989 and 1995, when the women were first diagnosed with early-stage breast cancer.
A decade later, 83 percent of those who had had adequate vitamin D blood levels were alive without extensive spread of their cancer, versus 79 percent of those whose vitamin D levels were insufficient and 69 percent of those who were deficient, as defined by widely used medical standards for measuring intake.
One red flag: The few women with the very highest levels of vitamin D seemed to have worse survival.
Though the study was too small and those results were not conclusive, "there may be an optimal level of vitamin D in women with breast cancer and it may be possible to take too much," Goodwin said.
The federal government says up to 2,000 international units of vitamin D a day seems OK. Taking 800 units per day will, on average, raise blood levels to the middle of the range that seems best for bone and general health, Goodwin said.
Vitamin D is in salmon and other oily fish, and milk is routinely fortified with it, but dietary sources account for little of the amount of D circulating in the blood, experts say.
"It's very hard to make a recommendation" because how much difference a supplement makes depends on someone's baseline level, which also can be affected by sunlight, skin type and time of year, she explained.
Doctors do suggest breast cancer patients get their vitamin D levels checked to see whether they are deficient. The simple blood test is available in many hospitals and labs for about $25, Goodwin said.
Dr. Nancy Davidson, a Johns Hopkins University cancer specialist who is president of the oncology society, said those tests are growing in popularity, even in ordinary medical care.
"Rightly or wrongly, I'm increasingly seeing physicians who are measuring this," she said.
The Canadian study was paid for by the Breast Cancer Research Foundation in New York, established by cosmetics magnate Evelyn Lauder.
"It's a very provocative paper. It's confirmatory of a tremendous amount of evidence that vitamin D is an important component of health," said Dr. Larry Norton, chief of breast cancer programs at Memorial Sloan-Kettering Cancer Center in New York and a medical adviser to the foundation.
Breast cancer is the most common cancer in women. About 184,450 cases and 40,930 deaths from the disease are expected in the United States this year.
On the Net:
Government vitamin information:
Cancer conference: http://www.asco.org
More information on the health benefits of Vitamin D. I have previously commented on the benefits of Vitamin D in previous newsletters, and a link to an excellent website on Vitamin D can be found at the Vitamin D Council website . There is ample information on this website about the cancer preventing benefits of Vitamin D. I highly recommend you look through the information.
Many physicians are hesitant to go against the grain and make nutritional or vitamin recommendations that are not echoed by either the majority of physicians or by large medical studies. But they usually join the crowd when it becomes mainstream.
I have been advocating Vitamin D supplementation to normal physiologic levels for the past few years. As Vitamin D is produced by our bodies in response to sunlight, it seems a very natural and safe alternative to good health! If a treatment, whether it be traditional or alternative, can help while doing no harm, then it is reasonable to try under monitoring and supervision.
At my office, “First Do No Harm”is side be side with “How can we keep you well with as little medication as possible”.
If you have questions on how to get the proper amount of Vitamin D, please contact my office.
Steven Horvitz, D.O.
Founder of The Institute for Medical Wellness
For past issues of the Newsletter please click here.
More information on Dr. Horvitz can be found at his website at www.DrHorvitz.com
Monday, May 12, 2008
Sun May 11, 7:01 PM ET
SUNDAY, May 11 (HealthDay News) -- When you're doing your spring cleaning, don't forget your nose.
Nasal irrigation is a cheap and easy way for people with spring allergies, nasal congestion, stuffy noses and post-nasal drip to get relief, says Dr. Melissa Pynnonen, co-director of the Michigan Sinus Center and an assistant professor in the University of Michigan's department of otolaryngology.
Nasal irrigation involves rinsing the nose and nasal passages with a solution made with a quarter-teaspoon of kosher salt, eight ounces of warm tap water and a quarter-teaspoon of baking soda.
There are a number of ways to administer the solution. For people who've never done nasal irrigation, Pynnonen recommended using an eight-ounce squeeze bottle and squirting four ounces of the solution into each nostril. The solutions exits through the opposite nostril. Opening your mouth and making a "K" sound will prevent the solution from coming out of your mouth.
Some people use a neti-pot, which looks like a miniature teapot. When using a neti-pot, the solution is poured, rather than squeezed, into the nose. Turkey basters or syringes like those used to suction a baby's nose also work.
"For most patients, the benefit of nasal irrigation is that it does a great job of treating symptoms that otherwise aren't well treated with medicine," Pynnonen said in a prepared statement. "Nasal irrigation can be considered a first-line treatment for common nasal and sinus symptoms. It's often more effective than medications," she concluded.
Nasal irrigation alone may be sufficient to control mild allergy symptoms in some people, but others may need to used medications in addition to nasal irrigation.
So long as children are old enough to cooperate, it's safe to give them nasal irrigation, using a smaller amount of solution, Pynnonen said.
Queen's University in Kingston, Ontario, Canada, has more about nasal irrigation.
One of the more common causes for visits to my office every May is allergies. When allergies get bad, people complain of sinus infections, asthma, losing their voices, headaches, and the overall misery of runny nose and itching. The best treatment for allergies is avoidance. A good handout on allergen avoidance can be found on my website at:
Neti pots have become more mainstream of recent. I have never used one, but many of my patient’s have. For a demonstration of a neti-pot in use please click on the following link for a you-tube demonstration.
Steven Horvitz, D.O.
Founder of The Institute for Medical Wellness